TBTA CAS 98946-18-0 tert-Butyl 2,2,2-Trichloroacetimidate Purity >95.0% (GC) Factory Protecting Reagent

Short Description:

tert-Butyl 2,2,2-Trichloroacetimidate

Synonyms: TBTA

CAS: 98946-18-0

Purity: >95.0% (GC)

Appearance: White Solid or Colorless Liquid

Protecting Reagents, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of tert-Butyl 2,2,2-Trichloroacetimidate (TBTA) (CAS: 98946-18-0) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase TBTA, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	tert-Butyl 2,2,2-Trichloroacetimidate
Synonyms	TBTA; 2,2,2-Trichloroacetimidic Acid tert-Butyl Ester; O-tert-Butyl Trichloroacetimidate
Stock Status	In Stock
CAS Number	98946-18-0
Molecular Formula	C6H10Cl3NO
Molecular Weight	218.50 g/mol
Melting Point	20.0~22.0℃(lit.)
Boiling Point	64.0~66.0℃/15 mmHg
Flash Point	55℃(131°F)
Density	1.221 g/mL at 25℃(lit.)
Refractive Index n20/D	1.456 (lit.)
Sensitive	Moisture Sensitive, Heat Sensitive
Solubility	Soluble in Organic Solvents, Cyclo Hexane
Storage Temp.	Cool & Dry Place (2~8℃)
COA & MSDS	Available
Category	Protecting Reagents
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	White Solid or Colorless Liquid	Complies
Melting Point	20.0~22.0℃	Complies
Purity / Analysis Method	>95.0% (GC)	96.8%
Infrared Spectrum	Conforms to Structure	Complies
Proton NMR Spectrum	Conforms to Structure	Complies
Conclusion	The product has been tested & complies with the specifications
Note	This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid)

Package/Storage/Shipping:

Package: Bottle, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Moisture sensitive. Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

98946-18-0 - Risk and Safety:

Risk Codes
R10 - Flammable
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S16 - Keep away from sources of ignition.
S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
UN IDs UN 1993 3/PG 3
WGK Germany 3
FLUKA BRAND F CODES 10-21
TSCA No
HS Code 2925290090
Hazard Note Irritant/Moisture Sensitive
Hazard Class 3.2
Packing Group III

Application:

tert-Butyl 2,2,2-Trichloroacetimidate (TBTA) (CAS: 98946-18-0) is used as a peptide synthesis reagent, protecting reagent.
Application tert-Butyl 2,2,2-trichloroacetimidate is used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.
Prepare to trichloroacetonitrile (100g, 0.69mol) in diethyl ether (69mL), add potassium tert-butoxide (69mL, 1M in tert-butanol) in diethyl ether (69mL) drop by drop, and maintain it at 0℃ 30 minutes. Then, the mixture is allowed to warm to room temperature during one hour, and then stirred for another hour under reflux heating. The mixture is cooled to room temperature and evaporated under reduced pressure to obtain oil. The oil was dissolved in hexane (140mL) and filtered to remove the potassium salt. The filtrate was evaporated under reduced pressure and the residual oil was purified by vacuum distillation. Fractions distilled at 2.4mmHg and 40℃ were collected to obtain the title compound (105g, 69%).